Nucleic Acids Structure and Force

Xiangyun Qiu
Associate Professor 
Department of Physics
George Washington University

Wed, September 26, 2018 - 4:00 PM
Karl Herzfeld Auditorium of Hannan Hall - Rm 108

The functional properties of materials are closely connected with their structures and the forces animating such structures, with the latter particularly important for biomolecules. Precise knowledge of biomolecular structure and force is thus critical to elucidating physical origins of biomolecular behaviors. We have a long-standing interest in how the force/structure-function relationships are manifested in the diverse family of nucleic acids, known as the blueprints of life. In this talk, I will introduce our main technique of x-ray/neutron scattering and how it is used to measure nucleic acids structure and force, and then discuss a few selective applications from systems such as densely packed DNA arrays in vitro and in viro, semi-dilute short DNA solutions, and oligomeric chromatin.

Refreshments served at 3:45 PM

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